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KMID : 0378019680110100071
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New Medical Journal
1968 Volume.11 No. 10 p.71 ~ p.74
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Properties of Gas Diffusion in Excised Cornea of Dog and Rabbit.
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Abstract
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Diffusion properly of the cornea to CO2 has studied in present report. Fresh cornea was excised from dog or rabbit and was tightly ligated to, the open end of a small glass capsule. The space of bigger glass box in which glass; capsule with cornea sample is contained was filled with pure CO2 under positive pressure of 3 mmHg. The other end´ of glass capsule was connected to two 10 nil syringes by two narrow polyethylen tubes and the total gas space of the capsule, tubes and syringes was arranged as to be 9 ml filled with room air.,
The volume of diffused COZ into ´the capsule from outer space was measured by analysis of the CO2 composition in the-capsule space. The diffusion rate of CO2 was measured at each 5th minute for 30 minutes of experiment.
Results obtained are summarized as follow:. "
1. In 9´samples of dog cornea, CO2 diffusion rate was 5.4 XW-3 ml/min/cmz in average of 30 minutes duration and in first ´5 minutes, -the diffusion rate was 7.87 X10-3 ml/min/emz.
In 4 samples of rabbit cornea, ~COZ diffusion rate was 7.54 X10^(-3 )ml/min/cmz in average of 30 minutes duration and was 10.5 X 10-3 ml/min/=2 in first 5 minutes.. 7
2., Diffusion coefficient of CO2 in dog cornea in first 5 minutes is calculated as 10.55 X10-4 cm2/min and permeation . coefficient of CO2 in dog cornea is calculated as 5.89 X 10-4 cui2/min/atm.
Diffusion coefficient´ and permeation coefficient of 02 in.dog cornea. is driven from those of´ .0O2. in dog
cornea and is estimated as 10.88 X 10-4 cm.2/min and 2.56 X 10^(-3)cm2/min/atm. respectively
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